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You may experience the benefits of pletal 2 to 4 weeks after beginning treatment.

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Cilostazol did not inhibit the pharmacologic effectsPTaPTTbleeding timeor platelet aggregationof Rand S-warfarin after a single 25-mg dose of warfarinThe effect of concomitant multiple dosing of warfarin and Pletal on the pharmacodynamics of both drugs is unknown.

Due to cilostazol’s platelet aggregation inhibitory effect it is possible that an increased bleeding risk occurs in combination with surgeryincluding minor invasive measurements like tooth extractionIf a patient is to undergo elective surgery and antiplatelet effect is not necessarycilostazol should be stopped 5 days prior to surgery.

Cilostazol is used to improve the symptoms of a certain blood flow problem in the legsintermittent claudicationCilostazol can decrease the muscle pain/cramps that occur during exercise/walkingClaudication pain is caused by too little oxygen getting to the musclesCilostazol can increase blood flow and the amount of oxygen that gets to the muscles.

The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongationBefore using cilostazoltell your doctor or pharmacist of all the drugs you take and if you have any of the following conditionscertain heart problemsheart failureslow heartbeatQT prolongation in the EKGfamily history of certain heart problemsQT prolongation in the EKGsudden cardiac death

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pletal is typically taken in 100mg doses twice a day.

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