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SELECTION CRITERIAAll randomised clinical trials comparing olanzapine to placebo or any antipsychotic treatment for those with schizophrenia or schizophreniform psychoses.

This document does not contain all possible interactionsThereforebefore using this producttell your doctor or pharmacist of all the products you useKeep a list of all your medications with youand share the list with your doctor and pharmacistCheck with your physician if you have health questions or concerns.

Olanzapine can be given without regards for meals as absorption is not affected by foodGradual tapering of the dose should be considered when discontinuing olanzapine.

Bipolar I DisorderManic or Mixed EpisodesOlanzapine as Adjunct to Lithium or ValproateIn a study of patients who were already tolerating either lithium or valproate as monotherapydiscontinuation rates due to adverse reactions were 11for the combination of oral olanzapine with lithium or valproate compared to 2for patients who remained on lithium or valproate monotherapyDiscontinuations with the combination of oral olanzapine and lithium or valproate that occurred in more than 1 patient weresomnolence3weight gain1and peripheral edema1

CiprofloxacinCiprodiltiazemCardizemDilacorTiazacerythromycinand fluvoxamineLuvoxmay have the opposite effectthat isthey may increase blood levels of olanzapineand the dose of olanzapine may need to be reduced.

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19 there is no specific, known antidote for olanzapine overdose, and even physicians are recommended to call a certified poison control center for information on the treatment of such a case.

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