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Notify your physician if you become pregnant while taking levothroid levothyroxine sodium .

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The mechanisms by which thyroid hormones exert their physiologic actions are not completely understoodbut it is thought that their principal effects are exerted through control of DNA transcription and protein synthesisT 3 and T 4 diffuse into the cell nucleus and bind to thyroid receptor proteins attached to DNAThis hormone nuclear receptor complex activates gene transcription and synthesis of messenger RNA and cytoplasmic proteins.

This is not a complete list of levothyroxine drug interactionsAsk your doctor or pharmacist for more information.

Levothyroxine is a tablet that is taken by mouthusually once a dayIt should be taken with a full glass of waterTake levothyroxine in the morning on an empty stomachat least one-half hour to one hour before eating any foodIron and calcium supplements and antacids can decrease the absorption of levothyroxine tabletsTake these products at least 4 hours before or 4 hours after you take levothyroxine.

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